Zelnorm: A Troubled Drug

What is Zelnorm?

Zelnorm was first placed on the market to treat women for irritable bowel syndrome(IBS). In August, 2004, Zelnorn was given the additional indication by the FDA for short term treatment of chronic constipation in men and women under the age of 65. Irritable bowel syndrome is a disorder that interferes the functions of the large intestine. Symptoms of IBS include cramps, abdominal pain, bloating, constipation, and diarrhea.

Novartis sales of Zelnorn in 2006 were $561 million, paying off with ease the $325 million Novartis spend on marking Zelnorm to doctors and patients of the last three years.

The Zelnorm Recall

In March, 2007, the FDA recommended that Zelnorm be removed from the market after reviewing the data from 29 different clinical trials involving Zelnorm that found that users of Zelnorm experience heart attacks, strokes and angina at a rate 7 to 8 times greater than those who took a placebo. Accordingly, the FDA determined that the risk of heart attack or other serious cardic injury required Zelnorm's removal from the market. Zelnorm remains on the market today for use in extreme IBS cases.

Taking Zelnorm off the market was the right idea. The drug's risks are unacceptable. But these comments underscore that the decision to take a drug off the market is complicted. Many people were being treated for IBS with Zelnorm were willing to take the risk of death - think about that - because the Zelnorm worked for them when other druges didn't..

Contact Us For a Free Consultation

1Free Consultation

2Available to talk NOW - 24/7

3No fees unless you WIN

Miller & Zois clients have received over $100 Million in verdicts and settlements. Let us fight for you!

Client Reviews

They quite literally worked as hard as if not harder than the doctors to save our lives.
Ron helped me find a clear path that ended with my foot healing and a settlement that was much more than I hope for. Aaron Johnson
Hopefully I won't need it again but if I do, I have definitely found my lawyer for life and I would definitely recommend this office to anyone! Bridget Stevens, Google User
The last case I referred to them settled for $1.2 million. John Selinger
I am so grateful that I was lucky to pick Miller & Zois. Maggie Lauer, Google User
The entire team from the intake Samantha to the lawyer himself (Ron Miller) has been really approachable. Suzette Allen, Google User
The case settled and I got a lot more money than I expected. Ron even fought to reduce how much I owed in medical bills so I could get an even larger settlement. Nchedo Idahosa