Ozempic is a popular drug for type-2 diabetes management and it is also popular for use as a weight loss drug. New evidence from the FDA has recently shown that taking Ozempic can significantly increase the risk of gastroparesis, a very serious gastrointestinal condition.
The manufacturer of Ozempic did not adequately warn patients and doctors about the risk of gallbladder disease. Individuals who used Ozempic and subsequently developed a serious gastrointestinal health condition may be able to file a product liability lawsuit and get financial compensation.
This page will provide the latest news and updates on the Ozempic litigation, as well as our predictions about the potential settlement value of these cases.
Ozempic lawsuits are being filed around the country. If you have an Ozempic lawsuit, call us today at 800-553-8082 or reach out to us online.
Ozempic Lawsuit Updates
Our law firm seeks to provide victims with the latest Ozempic lawsuit updates. We update this page frequently to bring you the latest news and information impacting your claim.
June 18, 2026 – Two Separate GLP-1 MDLs Are Now Driving the Litigation
The Ozempic litigation has now split into two major tracks. The original GLP-1 MDL, MDL No. 3094, focuses mainly on gastrointestinal injuries such as gastroparesis, ileus, bowel obstruction, and related complications. A newer MDL, MDL No. 3163, focuses on NAION vision loss claims involving Ozempic, Wegovy, Mounjaro, Trulicity, Zepbound, and other GLP-1 drugs.
This split makes sense. The stomach paralysis cases and the blindness cases are very different lawsuits. Gastroparesis claims are about delayed gastric emptying, chronic nausea, vomiting, hospitalizations, feeding problems, and long-term GI damage. NAION claims are about sudden vision loss, often permanent, from reduced blood flow to the optic nerve. Both theories are serious, but they require different experts, different medical proof, and different trial stories.
For plaintiffs, this is probably a good development. The NAION cases should not be buried inside the GI injury litigation. Sudden vision loss is a cleaner and more dramatic injury, and juries will immediately understand the harm. The GI cases remain important, but the vision loss claims create a different kind of settlement pressure because the injury is visible, permanent, and easier to explain.
June 15, 2026 – GLP-1 GI Injury MDL Reaches 3,763 Pending Cases
The federal GLP-1 gastrointestinal injury MDL continues to grow. As of June 2026, there are 3,763 pending cases in MDL No. 3094. These lawsuits involve claims that Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus, and similar GLP-1 drugs caused severe gastrointestinal injuries and that the manufacturers failed to provide adequate warnings.
The case count tells us that because it shows that this litigation is not fading. The defense would love to frame these claims as isolated complaints from people who simply had normal side effects from weight loss drugs. But thousands of lawsuits tell a different story. The central issue is whether the labels and warnings gave doctors and patients enough information about serious risks like gastroparesis, bowel obstruction, ileus, and related complications.
June 12, 2026 – NAION Vision Loss MDL Grows to 110 Cases
The newer GLP-1 NAION MDL is also growing. As of June 2026, there are 110 pending cases in MDL No. 3163. That number is still much smaller than the gastrointestinal injury MDL, but the NAION claims are likely to become the centerpiece of the GLP-1 litigation.
The key question will be general causation. Plaintiffs have strong emerging science, including studies tying semaglutide to a higher risk of NAION. The defense will argue that diabetes, obesity, age, blood pressure, sleep apnea, and vascular risk factors also contribute to NAION. That is the battle.
June 10, 2026 – Expert Hearing Set for September in GLP-1 GI Injury MDL
The next major event in the GLP-1 gastrointestinal injury litigation is expected to be a Rule 702 expert hearing in September 2026. That hearing is a big deal because it will help determine what expert testimony plaintiffs can use to prove that GLP-1 drugs caused their injuries.
This is the stage where the defense tries to narrow the case before it ever gets to a jury. Novo Nordisk and Eli Lilly will attack the reliability of plaintiff experts, challenge causation opinions, and argue that gastroparesis and other GI injuries are too complicated or too multifactorial to blame on the drugs. Plaintiffs will argue that the science, the mechanism, the labeling history, and the real-world injury reports support letting juries hear the evidence.
These hearings can change the direction of a mass tort. If plaintiffs survive the expert challenges in good shape, settlement pressure goes up. If the defense knocks out key experts, the litigation gets harder. So September 2026 may be one of the most important months yet for Ozempic, Wegovy, Mounjaro, and Zepbound GI injury claims.
About Ozempic
Ozempic is the brand name for semaglutide, an antidiabetic medication that is primarily used for the treatment and management of type-2 diabetes. Ozempic works by prompting the body to increase insulin secretion and the disposal of blood sugar, which improves glycemic control.
Although Ozempic is only approved for use in the treatment of diabetes, it has recently gain popularity for off-label use as a weight loss and anti-obesity drug. Ozempic is typically taken in the form of injections 2 times per month.
Ozempic was developed by Novo Nordisk, an international pharmaceutical company headquartered in Denmark that specializes in medications for the treatment of diabetes. Novo Nordisk first developed Ozempic in 2012 and it was approved for use by the FDA and released on the U.S. market in late 2017.
In 2021, a higher-dose version of Ozempic (sold under the brand name Wegovy) was approved by the FDA.
Crazy History of How Ozempic Happened
In the early 1990s, Novo Nordisk researchers discovered that liraglutide, a GLP-1 (glucagon-like peptide-1) agonist, caused rats to almost completely stop eating when injected with the compound. GLP-1 agonists are medications that help lower blood sugar levels and promote weight loss by mimicking the naturally occurring GLP-1 hormone. These drugs bind to GLP receptors, triggering the effects of the GLP-1 hormone, with higher doses resulting in more pronounced effects.
One Novo Nordisk scientist, Lotte Bjerre Knudsen, noted that the rats “starved themselves,” indicating a significant role of these peptides in appetite regulation. Subsequent testing in humans revealed that those receiving a GLP-1 agonist ate 12% less at a lunch buffet compared to those who received a placebo. Based on these findings, Novo Nordisk decided to study liraglutide not only as a diabetes drug but also as a potential treatment for obesity.
In 2010, liraglutide was approved by the FDA for diabetes treatment under the brand name Victoza. Following this, Novo Nordisk continued to study the drug for weight loss. After clinical trials, the FDA approved liraglutide for obesity treatment in 2014, marketed as Saxenda. Despite the modest weight loss effects of Saxenda, Novo Nordisk developed a new molecule, semaglutide, aiming for a longer-lasting GLP-1 agonist that patients would not need to inject daily.
Semaglutide was branded as Ozempic, and Novo Nordisk submitted a new drug application to the FDA for regulatory approval of a once-weekly injectable treatment for Type 2 diabetes in 2016. The FDA approved Ozempic in 2017, and the drug demonstrated a 15% weight loss in addition to diabetic control, significantly higher than Saxenda’s effects.
In 2021, Novo Nordisk completed clinical trials studying semaglutide for weight loss, and the results showed sustained, clinically relevant reductions in body weight for overweight and obese participants. Theres is a reason for the Ozempic craze – largely, the durg works. But the trial data also highlighted gastrointestinal events, with a higher discontinuation rate in the semaglutide group due to these events.
How Ozempic Works
Ozempic works by mimicking the function of GLP-1. After a person eats, the body’s natural response is to release insulin to manage the increase in blood sugar. In people with type 2 diabetes, this system may not function effectively, leading to high blood sugar levels. Ozempic triggers insulin production after meals, reducing blood sugar levels.
It also slows down digestion, which helps to lower glucose levels in the blood further. Furthermore, it decreases the amount of glucose produced by the liver, maintaining a balance in the blood sugar levels.
Credit where credit is due – the drug works. But the question is whether everyone should use it given the risks. That is what this litigation is about.
Clinical Use
This medication is usually prescribed when diet and exercise alone do not provide adequate control of blood sugar levels in people with type 2 diabetes. It may be used as a standalone treatment or in combination with other diabetic medications such as metformin. It is not used for treating type 1 diabetes or for people with diabetic ketoacidosis.
Administration and Dosage
Ozempic is not a pill but a subcutaneous injection, typically given once a week. It’s injected into the skin of the abdomen, thigh, or upper arm.
The initial dosage is usually 0.25 mg per week for the first month, serving as a period for the body to adjust to the medication. This dose is then increased to 0.5 mg per week.
Depending on the patient’s response and tolerability, the dose may be further increased to a maximum of 1 mg per week.
Side Effects
As with any medication, Ozempic comes with potential side effects. The most common ones include nausea, vomiting, diarrhea, abdominal pain, and constipation.
Many of these side effects are more common when a person first starts taking the drug and may lessen over time.
Other side effects may include reduced appetite, indigestion, bloating, and fatigue. More severe but less common side effects include pancreatitis, changes in vision, and kidney problems.
This is a good time to cull out the side effects our Ozempic lawyers think are injuries that may lead to settlements because while the defendants might not agree, we believe are related to Ozempic:
Gastroparesis or Stomach Paralysis from Using Ozempic
Gastroparesis, also known as stomach paralysis, can occur from using Ozempic. This condition affects normal muscle movement in the stomach, slowing down or stopping the movement of food from the stomach to the small intestine, causing severe digestive issues. Symptoms include nausea, vomiting, abdominal pain, bloating, and a feeling of fullness after eating just a few bites. It can lead to serious complications such as malnutrition, dehydration, and fluctuations in blood sugar levels. This is the signature injury for 95% of plaintiffs in this litigation right now. Our Ozempic lawyers flush this injury out more below.
Gastrointestinal Issues Requiring Overnight Hospitalization from Using Ozempic
Patients using Ozempic may experience severe gastrointestinal issues that necessitate overnight hospitalization. These issues can include intense abdominal pain, persistent vomiting, severe dehydration, and other complications that require medical intervention and monitoring.
Esophageal Damage Necessitating Surgical Intervention from Using Ozempic
Esophageal damage can occur from using Ozempic, requiring surgical intervention. This damage may be due to severe inflammation, tears, or other complications within the esophagus, leading to difficulty swallowing, pain, and increased risk of infection.
Ileus or Bowel Obstruction from Using Ozempic
Ileus or bowel obstruction involves a blockage in the intestines that prevents the normal movement of digestive contents. Symptoms include severe abdominal pain, vomiting, constipation, and inability to pass gas. This condition, which can result from using Ozempic, can lead to significant complications and often requires surgical treatment to remove the obstruction.
Pulmonary Aspiration from Using Ozempic
Pulmonary aspiration occurs when food, liquid, or other substances are inhaled into the lungs instead of being swallowed into the esophagus. This can cause serious respiratory issues, including pneumonia and other infections, and may require medical intervention. Pulmonary aspiration can be a complication of using Ozempic.
Gallbladder Injury Necessitating Surgery from Using Ozempic
Many patients experiencd gallbladder injury necessitating surgical intervention. This includes conditions such as gallstones, cholecystitis (inflammation of the gallbladder), and other gallbladder-related complications that require removal of the gallbladder. Our Ozempic lawyers are only taking these cases if the patientbegan using Ozempic in 2021 or earlier.
Deep Vein Thrombosis (DVT) and Related Complications, Including Death from Using Ozempic
Sudden Vision Loss or Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) from Using Ozempic
This is a new one based on a study that came out in July 2024 that we talk about in the comments above. Sudden vision loss can occur from using Ozempic due to nonarteritic anterior ischemic optic neuropathy (NAION), a condition where blood flow to the optic nerve is reduced. This can lead to permanent vision loss in one or both eyes and requires immediate medical attention to prevent further damage.
Ozempic Linked to Gastroparesis
At the center of the Ozempic lawsuits is new evidence showing that prolonged and/or high dose use of Ozempic (and related drugs) is linked to a serious health condition called gastroparesis. An estimated 95% of the lawsuits in the Ozempic MDL involve gastroparesis.
Gastroparesis is a medical condition that affects the normal movement of the muscles in the stomach, leading to delayed emptying of food from the stomach into the small intestine. Normally, after consuming food, the stomach contracts to break down the food and then moves it into the small intestine for further digestion and absorption of nutrients.
In gastroparesis, this process is disrupted due to nerve damage or muscle dysfunction that affects the stomach’s ability to contract properly. As a result, food remains in the stomach for an extended period, causing symptoms such as:
1. Nausea and vomiting: Food that stays in the stomach can cause feelings of fullness, bloating, and nausea, leading to vomiting in some cases.
2. Early satiety: Feeling full quickly when eating, even with small amounts of food.
3. Abdominal pain or discomfort: This can be caused by the distension of the stomach due to delayed emptying.
4. Heartburn or gastroesophageal reflux: Delayed emptying of the stomach can lead to backup of stomach acid into the esophagus, causing symptoms of reflux.
5. Changes in blood sugar levels: In diabetic individuals, gastroparesis can affect blood sugar control because the digestion and absorption of carbohydrates are delayed.
Treatment of gastroparesis aims to relieve symptoms and improve stomach emptying. This may involve dietary modifications (such as eating smaller, more frequent meals of low-fiber and low-fat foods), medications to stimulate stomach emptying or control symptoms like nausea and vomiting, and sometimes procedures or surgery in severe cases.
Management often requires a multidisciplinary approach involving gastroenterologists, dietitians, and other specialists to tailor treatment to the individual’s needs.
What Are the Ozempic Lawsuits Really About?
In the lawsuit against Novo Nordisk regarding Ozempic, the main complaint is that the company didn’t properly warn doctors and patients about the risk of gastroparesis, a serious stomach condition, when taking the drug. That is the big issue. The label on Ozempic does mention some effects on stomach emptying but doesn’t specifically say that gastroparesis is a risk.
The company’s website also doesn’t include this risk in its safety information section.
Previously, the Ozempic label had a section advising doctors to tell patients about common side effects like nausea and vomiting.
However, this section was removed in 2020. This is important because ongoing vomiting can be a sign of gastroparesis. The label also used to say that vomiting usually decreases over time, which could lead doctors to overlook gastroparesis symptoms.
The Ozempic lawsuit also drills down on the idea that Ozempic’s label advises women to stop using the drug at least two months before planning a pregnancy. This indicates that the effects of the drug, like vomiting, can last for a while after stopping it. This point is effectively used to argue that Novo Nordisk should have been more upfront about the risk of gastroparesis and its long-lasting effects.
Since Ozempic was approved, Novo Nordisk is accused of not providing adequate warnings about the link between Ozempic and gastroparesis. The lawsuit claims that the company knew or should have known about this risk based on clinical studies and medical literature. Despite this knowledge, it’s alleged that they didn’t warn the medical community or patients properly.
If Novo Nordisk had provided clear warnings, the lawsuit argues, doctors might have made different decisions about prescribing Ozempic or would have monitored patients more closely for gastroparesis symptoms, potentially avoiding the condition.
The Science
In August 2022, a Research Letter published in the journal JAMA Internal Medicine revealed that Ozempic (and other similar drugs) appeared to be linked to higher rates of gallbladder problems such as gallstones and acute gallbladder disease. The findings were based on a review conducted by the Food and Drug Administration using data from the FDA Adverse Event Reporting System (FAERS).
The FDA data showed that individuals who used Ozempic for type-2 diabetes treatment displayed a significantly higher rate of gallbladder health conditions, particularly acute gallbladder disease (acute cholecystitis).
Acute gallbladder disease is characterized by sudden inflammation of the gallbladder. It is usually caused by gallstones blocking the tube leading out of the gallbladder.
It is a serious condition that must be treated in the hospital to avoid further injury. In many cases, treatment involves surgical removal of the gallbladder.
The study concluded that there was an increased risk of both gallstones (cholelithiasis) (RR 1.27; and acute gallbladder disease (cholecystitis) with Ozempic compared to placebo or active comparator.
The researchers also concluded that the risk of gallbladder problems from Ozempic was higher when the drug was at higher doses, for longer durations, and when the drug was used for weight loss.
The conclusions published in the 2022 Research Letter were consistent with findings in two prior meta-analysis studies on an association between drugs like Ozempic and gallbladder problems and gallstones. These prior studies were published in Diabetes Research and Clinical Practice (2020) and Diabetes, Obesity & Metabolism (2017).
October 2023 Study
A recent study investigated how certain diabetes drugs, such as Ozempic and Liraglutide, affect people when used for weight loss, a purpose different from their original design. This study provides ample fodder for every Ozempic lawsuit.
The research was conducted by a team from the University of British Columbia, Canada, and the results were published in the Journal of the American Medical Association (JAMA).
The study included a substantial sample size, analyzing the medical records of 16 million patients from 2006 to 2020, using the PharMetrics Plus for Academics database. This database captures a large proportion of outpatient prescriptions and physician diagnoses in the U.S.
What did they find? They found exactly what Ozempic lawyers thought they would find.
The study found that those who used diabetes drugs for shedding pounds were at a higher risk of developing several stomach-related issues. These included pancreatitis, a condition where the pancreas becomes inflamed and painful; gastroparesis, a disorder that slows or stops the movement of food from the stomach to the intestines; and bowel obstruction, a blockage in the intestines.
However, the study did not link these diabetes medications to an increased risk of biliary disease, which affects the gallbladder and bile ducts.
The findings showed an increased risk of several gastrointestinal issues in patients using GLP-1 agonists for weight loss compared to those using bupropion-naltrexone. These adverse events included pancreatitis (inflammation of the pancreas), gastroparesis (delayed stomach emptying), and bowel obstruction, but not biliary disease (issues related to the gallbladder and bile ducts).
For instance, the incidence rates per 1000 person-years for biliary disease were 18.6 for liraglutide, 11.7 for semaglutide, and 12.6 for bupropion-naltrexone. For pancreatitis, the incidence rates were 7.9 for liraglutide, 4.6 for semaglutide, and 1.0 for bupropion-naltrexone.
Ozempic Risks Were Known for a Long Time
The studies we cite about are among the strongest studies. But the knowledge of the risk go back much further.
A 2016 trial funded by Novo Nordisk on semaglutide and cardiovascular outcomes in type 2 diabetes patients revealed more gastrointestinal disorders in the semaglutide group compared to the placebo group.
These included severe adverse events like impaired gastric emptying, abdominal pain, vomiting, diarrhea, and intestinal obstruction.
In the trial, two subjects permanently discontinued treatment due to moderate impaired gastric emptying, and three reported mild events of the same during the semaglutide run-in period. This was a clue, certainly not that first clue, of the stomach complications with Ozempic.
A study published in 2017 added more concern, nothing that GLP-1 receptor agonists (GLP-1RAs) like semaglutide suppress gastric emptying by inhibiting stomach peristalsis while increasing contraction of the pyloric region.
Yet another 2017 study surveyed 10,987 patients and 851 physicians, finding gastrointestinal issues were the top reasons for discontinuing GLP-1RAs, with many patients reporting symptoms of gastroparesis, such as feeling sick and vomiting.
Further studies and medical literature, including those in 2019 and 2020, identified adverse events like diabetic gastroparesis and emphasized that some patients might not know they have gastroparesis until starting GLP-1RA therapy.
A 2021 article in the Journal of Investigative Medicine highlighted the importance of identifying causative drugs for gastroparesis, especially since both diabetes and GLP-1RAs can delay gastric emptying, complicating diagnosis and treatment.
Ozempic Lawsuit Settlement Amounts
It is way too early in the litigation to make any meaningful estimations of the potential settlement value of Ozempic gastroparesis injury lawsuits. These claims are very new, and the admissibility of the scientific causation evidence has not yet been tested.
Our lawyers can, however, make an educated guess as to the potential settlement value range for these cases based on prior settlements in cases involving similar injuries.
Assuming that the causation evidence holds and these cases are otherwise successful, we think that the average settlement amounts of the top-tier Ozempic lawsuits could be $400,000 to $700,000.
The top tier cases will primarily be those in which the plaintiff developed gastroparesis and suffered serious health complications as a result. But if the science pans out on these NAION vision loss claims, you could see settlement values that go far beyond gastroparesis.
Most Ozempic lawsuits will not have meaningful lifelong injuries. The average Ozempic settlement payout will be much lower than $400,000.
Get an Ozempic Lawyer
Ozempic lawsuits are being filed around the country. If you have an Ozempic lawsuit, now is the time to act. Call our attorneys today at 800-553-8082 or reach out to us online.
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